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An oligodeoxyribonucleotide N3'--> P5' phosphoramidate duplex forms an A-type helix in solution.

The solution conformations of the dinucleotide d(TT) and the modified duplex d(CGCGAATTCGCG)2 with N3'--> P5' phosphoramidate internucleoside linkages have been studied using circular dichroism (CD) and NMR spectroscopy. The CD spectra indicate that the duplex conformation is similar to that of isos...

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Udgivet i:Nucleic Acids Res
Principais autores: Ding, D, Grayaznov, S M, Lloyd, D H, Chandrasekaran, S, Yao, S, Ratmeyer, L, Pan, Y, Wilson, W D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.354
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