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An oligodeoxyribonucleotide N3'--> P5' phosphoramidate duplex forms an A-type helix in solution.

The solution conformations of the dinucleotide d(TT) and the modified duplex d(CGCGAATTCGCG)2 with N3'--> P5' phosphoramidate internucleoside linkages have been studied using circular dichroism (CD) and NMR spectroscopy. The CD spectra indicate that the duplex conformation is similar to that of isos...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Ding, D, Grayaznov, S M, Lloyd, D H, Chandrasekaran, S, Yao, S, Ratmeyer, L, Pan, Y, Wilson, W D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.354
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