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A clustering property of highly-degenerate transcription factor binding sites in the mammalian genome

Transcription factor binding sites (TFBSs) are short DNA sequences interacting with transcription factors (TFs), which regulate gene expression. Due to the relatively short length of such binding sites, it is largely unclear how the specificity of protein–DNA interaction is achieved. Here, we have p...

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Detalhes bibliográficos
Main Authors: Zhang, Chaolin, Xuan, Zhenyu, Otto, Stefanie, Hover, John R., McCorkle, Sean R., Mandel, Gail, Zhang, Michael Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456330/
https://ncbi.nlm.nih.gov/pubmed/16670430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl248
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