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Estimating Selection on Nonsynonymous Mutations
The distribution of mutational effects on fitness is of fundamental importance for many aspects of evolution. We develop two methods for characterizing the fitness effects of deleterious, nonsynonymous mutations, using polymorphism data from two related species. These methods also provide estimates...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456207/ https://ncbi.nlm.nih.gov/pubmed/16299397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047217 |
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