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Growth Defect and Mutator Phenotypes of RecQ-Deficient Neurospora crassa Mutants Separately Result From Homologous Recombination and Nonhomologous End Joining During Repair of DNA Double-Strand Breaks

RecQ helicases function in the maintenance of genome stability in many organisms. The filamentous fungus Neurospora crassa has two RecQ homologs, QDE3 and RECQ2. We found that the qde-3 recQ2 double mutant showed a severe growth defect. The growth defect was alleviated by mutation in mei-3, the homo...

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書目詳細資料
Main Authors: Kato, Akihiro, Inoue, Hirokazu
格式: Artigo
語言:Inglês
出版: Copyright © 2006 by the Genetics Society of America 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456140/
https://ncbi.nlm.nih.gov/pubmed/16219790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.041756
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