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Saccharomyces cerevisiae Ub-Conjugating Enzyme Ubc4 Binds the Proteasome in the Presence of Translationally Damaged Proteins
Surveillance mechanisms that monitor protein synthesis can promote rapid elimination of misfolded nascent proteins. We showed that the translation elongation factor eEF1A and the proteasome subunit Rpt1 play a central role in the translocation of nascent-damaged proteins to the proteasome. We show h...
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456077/ https://ncbi.nlm.nih.gov/pubmed/16118187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.046888 |
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