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Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

Expression of the breast and ovarian cancer susceptibility gene BRCA1 is down-regulated in sporadic breast and ovarian cancer cases. Therefore, the identification of genes involved in the regulation of BRCA1 expression might lead to new insights into the pathogenesis and treatment of these tumors. I...

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Detalhes bibliográficos
Main Authors: Beger, Carmela, Pierce, Leigh N., Krüger, Martin, Marcusson, Eric G., Robbins, Joan M., Welcsh, Piri, Welch, Peter J., Welte, Karl, King, Mary-Claire, Barber, Jack R., Wong-Staal, Flossie
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14556/
https://ncbi.nlm.nih.gov/pubmed/11136250
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