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5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis

A cloverleaf structure at the 5′ terminus of poliovirus RNA binds viral and cellular proteins. To examine the role of the cloverleaf in poliovirus replication, we determined how cloverleaf mutations affected the stability, translation and replication of poliovirus RNA in HeLa S10 translation–replica...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Barton, David J., O’Donnell, Brian J., Flanegan, James B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.6.1439
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