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5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis

A cloverleaf structure at the 5′ terminus of poliovirus RNA binds viral and cellular proteins. To examine the role of the cloverleaf in poliovirus replication, we determined how cloverleaf mutations affected the stability, translation and replication of poliovirus RNA in HeLa S10 translation–replica...

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Bibliographic Details
Main Authors: Barton, David J., O’Donnell, Brian J., Flanegan, James B.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC145522/
https://ncbi.nlm.nih.gov/pubmed/11250909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1439
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