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Murine CD59a Modulates Anti-Viral CD4(+) T Cell Activity in a Complement-Independent Manner

CD59 blocks formation of the membrane attack complex of complement by inhibiting binding of C9 to the C5b-8 complex. To investigate a role for CD59 in promoting T cell responses, we compared T cell activation in CD59a-deficient (Cd59a(−/−)) and wild-type (WT) mice after in vitro stimulation and afte...

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Autori principali: Longhi, M. Paula, Sivasankar, B., Omidvar, Nader, Morgan, B. Paul, Gallimore., Awen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1455165/
https://ncbi.nlm.nih.gov/pubmed/16301611
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