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Turning a disulfide isomerase into an oxidase: DsbC mutants that imitate DsbA

There are two distinct pathways for disulfide formation in prokaryotes. The DsbA–DsbB pathway introduces disulfide bonds de novo, while the DsbC–DsbD pathway functions to isomerize disulfides. One of the key questions in disulfide biology is how the isomerase pathway is kept separate from the oxidas...

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Udgivet i:EMBO J
Principais autores: Bader, Martin W., Hiniker, Annie, Regeimbal, James, Goldstone, David, Haebel, Peter W., Riemer, Jan, Metcalf, Peter, Bardwell, James C.A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.7.1555
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