Turning a disulfide isomerase into an oxidase: DsbC mutants that imitate DsbA

There are two distinct pathways for disulfide formation in prokaryotes. The DsbA–DsbB pathway introduces disulfide bonds de novo, while the DsbC–DsbD pathway functions to isomerize disulfides. One of the key questions in disulfide biology is how the isomerase pathway is kept separate from the oxidas...

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Publicat a:	EMBO J
Autors principals:	Bader, Martin W., Hiniker, Annie, Regeimbal, James, Goldstone, David, Haebel, Peter W., Riemer, Jan, Metcalf, Peter, Bardwell, James C.A.
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2001
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285220/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.7.1555
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