The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways

Dictyostelium discoideum DdRacGap1 (DRG) contains both Rho-GEF and Rho-GAP domains, a feature it shares with mammalian Bcr and Abr. To elucidate the physiological role of this multifunctional protein, we characterized the enzymatic activity of recombinant DRG fragments in vitro, created DRG-null cel...

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Detalles Bibliográficos
Main Authors: Knetsch, Menno L.W., Schäfers, Nicole, Horstmann, Heinz, Manstein, Dietmar J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC145496/
https://ncbi.nlm.nih.gov/pubmed/11285226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1620
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