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The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways
Dictyostelium discoideum DdRacGap1 (DRG) contains both Rho-GEF and Rho-GAP domains, a feature it shares with mammalian Bcr and Abr. To elucidate the physiological role of this multifunctional protein, we characterized the enzymatic activity of recombinant DRG fragments in vitro, created DRG-null cel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145496/ https://ncbi.nlm.nih.gov/pubmed/11285226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1620 |
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