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A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

The molecular mechanism(s) that are responsible for suppressing MyoD’s transcriptional activities in undifferentiated skeletal muscle cells have not yet been determined. We now show that MyoD associates with a histone deacetylase-1 (HDAC1) in these cells and that this interaction is responsible for...

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Autori principali: Mal, Asoke, Sturniolo, Michael, Schiltz, R.Louis, Ghosh, Mrinal K., Harter, Marian L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC145490/
https://ncbi.nlm.nih.gov/pubmed/11285237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1739
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