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A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

The molecular mechanism(s) that are responsible for suppressing MyoD’s transcriptional activities in undifferentiated skeletal muscle cells have not yet been determined. We now show that MyoD associates with a histone deacetylase-1 (HDAC1) in these cells and that this interaction is responsible for...

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Detalhes bibliográficos
Main Authors: Mal, Asoke, Sturniolo, Michael, Schiltz, R.Louis, Ghosh, Mrinal K., Harter, Marian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145490/
https://ncbi.nlm.nih.gov/pubmed/11285237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1739
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