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A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program
The molecular mechanism(s) that are responsible for suppressing MyoD’s transcriptional activities in undifferentiated skeletal muscle cells have not yet been determined. We now show that MyoD associates with a histone deacetylase-1 (HDAC1) in these cells and that this interaction is responsible for...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145490/ https://ncbi.nlm.nih.gov/pubmed/11285237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1739 |
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