Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

Alternative splicing of human cystic fibrosis transmembrane conductance regulator (CFTR) exon 9 is regulated by a combination of cis-acting elements distributed through the exon and both flanking introns (IVS8 and IVS9). Several studies have identified in the IVS8 intron 3′ splice site a regulatory...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Buratti, Emanuele, Dörk, Thilo, Zuccato, Elisabetta, Pagani, Franco, Romano, Maurizio, Baralle, Francisco E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.7.1774
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