Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

Alternative splicing of human cystic fibrosis transmembrane conductance regulator (CFTR) exon 9 is regulated by a combination of cis-acting elements distributed through the exon and both flanking introns (IVS8 and IVS9). Several studies have identified in the IVS8 intron 3′ splice site a regulatory...

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Main Authors: Buratti, Emanuele, Dörk, Thilo, Zuccato, Elisabetta, Pagani, Franco, Romano, Maurizio, Baralle, Francisco E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC145463/
https://ncbi.nlm.nih.gov/pubmed/11285240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1774
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