Código QR (código de barras bidimensional)

Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

Summary: TDP-43 nuclear clearance and cytoplasmic aggregation are hallmarks of TDP-43 proteinopathies. We recently demonstrated that binding to endogenous nuclear GU-rich RNAs sequesters TDP-43 in the nucleus by restricting its passive nuclear export. Here, we tested the feasibility of synthetic RNA...

Fuld beskrivelse

Na minha lista:
Principais autores: Xi Zhang, Tanuza Das, Tiffany F. Chao, Vickie Trinh, Rogger P. Carmen-Orozco, Jonathan P. Ling, Petr Kalab, Lindsey R. Hayes
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:iScience
Fag:
biochemistry
genetics
molecular biology
neuroscience
cell biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224013348
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker