An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria

Infections with parasitic helminths are important causes of morbidity and mortality worldwide. New drugs that are parasite specific and minimally toxic to the host are needed to counter these infections effectively. Here we report the finding of a previously unidentified compound, nafuredin, from As...

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Main Authors: Ōmura, Satoshi, Miyadera, Hiroko, Ui, Hideaki, Shiomi, Kazuro, Yamaguchi, Yuuichi, Masuma, Rokuro, Nagamitsu, Tohru, Takano, Daisuke, Sunazuka, Toshiaki, Harder, Achim, Kölbl, Heinz, Namikoshi, Michio, Miyoshi, Hideto, Sakamoto, Kimitoshi, Kita, Kiyoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2001
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14544/
https://ncbi.nlm.nih.gov/pubmed/11120889
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