Azithromycin Inhibits the Formation of Flagellar Filaments without Suppressing Flagellin Synthesis in Salmonella enterica Serovar Typhimurium

The present study shows that a sub-MIC of the macrolide antibiotic azithromycin (AZM) diminishes the virulence function of Salmonella enterica serovar Typhimurium. We first constructed an AZM-resistant strain (MS248) by introducing ermBC, an erythromycin ribosome methylase gene, into serovar Typhimu...

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Main Authors: Matsui, Hidenori, Eguchi, Masahiro, Ohsumi, Katsufumi, Nakamura, Akio, Isshiki, Yasunori, Sekiya, Kachiko, Kikuchi, Yuji, Nagamitsu, Tohru, Masuma, Rokuro, Sunazuka, Toshiaki, Omura, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
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Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196272/
https://ncbi.nlm.nih.gov/pubmed/16048953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3396-3403.2005
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