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The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

The yeast UPF1, UPF2 and UPF3 genes encode trans-acting factors of the nonsense-mediated mRNA decay pathway. In addition, the upf1Δ strain demonstrates a nonsense suppression phenotype and Upf1p has been shown to interact with the release factors eRF1 and eRF3. In this report, we show that both upf2...

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Pubblicato in:EMBO J
Autori principali: Wang, Weirong, Czaplinski, Kevin, Rao, Yu, Peltz, Stuart W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.880
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