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The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

The yeast UPF1, UPF2 and UPF3 genes encode trans-acting factors of the nonsense-mediated mRNA decay pathway. In addition, the upf1Δ strain demonstrates a nonsense suppression phenotype and Upf1p has been shown to interact with the release factors eRF1 and eRF3. In this report, we show that both upf2...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Wang, Weirong, Czaplinski, Kevin, Rao, Yu, Peltz, Stuart W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.880
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