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The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

The yeast UPF1, UPF2 and UPF3 genes encode trans-acting factors of the nonsense-mediated mRNA decay pathway. In addition, the upf1Δ strain demonstrates a nonsense suppression phenotype and Upf1p has been shown to interact with the release factors eRF1 and eRF3. In this report, we show that both upf2...

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Detalhes bibliográficos
Main Authors: Wang, Weirong, Czaplinski, Kevin, Rao, Yu, Peltz, Stuart W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145432/
https://ncbi.nlm.nih.gov/pubmed/11179232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.4.880
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