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F1 mice make two species of antigen-specific, parental haplotype-restricted, T-helper factor whose restrictions correspond to the phenotype of the I-A determinants that they bear.
Antigen-specific T-helper factor (ThF) bears I-A determinants and is I-A restricted in its action. This I-A restriction may be explained by ThF binding, and hence approximating antigen to its own I-A determinants, thereby facilitating recognition by the T cell (I-A presentation theory), or by a reco...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1454129/ https://ncbi.nlm.nih.gov/pubmed/2444530 |
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