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F1 mice make two species of antigen-specific, parental haplotype-restricted, T-helper factor whose restrictions correspond to the phenotype of the I-A determinants that they bear.

Antigen-specific T-helper factor (ThF) bears I-A determinants and is I-A restricted in its action. This I-A restriction may be explained by ThF binding, and hence approximating antigen to its own I-A determinants, thereby facilitating recognition by the T cell (I-A presentation theory), or by a reco...

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Hlavní autoři: Little, J A, Asherson, G L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454129/
https://ncbi.nlm.nih.gov/pubmed/2444530
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