Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding

eIF3 binds to 40S ribosomal subunits and stimulates recruitment of Met-tRNA(i)(Met) and mRNA to the pre-initiation complex. Saccharomyces cerevisiae contains an ortholog of human eIF3 subunit p35, HCR1, whose interactions with yeast eIF3 are not well defined. We found that HCR1 has a dual function i...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Valášek, Leoš, Phan, Lon, Schoenfeld, Lori W., Valášková, Věra, Hinnebusch, Alan G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.891
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