Induction by Sphingomyelinase of Shiga Toxin Receptor and Shiga Toxin 2 Sensitivity in Human Microvascular Endothelial Cells

Shiga toxin-producing enterohemorrhagic Escherichia coli is the major cause of acute renal failure in young children. The interaction of Shiga toxins 1 and 2 (Stx1 and Stx2) with endothelial cells is an important step in the renal coagulation and thrombosis observed in hemolytic uremic syndrome. Pre...

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Bibliographische Detailangaben
Hauptverfasser: Obrig, T. G., Seaner, R. M., Bentz, M., Lingwood, C. A., Boyd, B., Smith, A., Narrow, W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145396/
https://ncbi.nlm.nih.gov/pubmed/12540565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.845-849.2003
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