Migration through the Extracellular Matrix by the Parasitic Protozoan Leishmania Is Enhanced by Surface Metalloprotease gp63

Leishmania species engineered to express high levels of the surface metalloprotease gp63 have enhanced capacity of migration through extracellular matrix in vitro. This correlates with gp63 degradation of extracellular matrix components, such as collagen type IV and fibronectin, and suggests an impo...

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Autori principali: McGwire, Bradford S., Chang, Kwang-Poo, Engman, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC145380/
https://ncbi.nlm.nih.gov/pubmed/12540585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.1008-1010.2003
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