Human Eosinophil Peroxidase Induces Surface Alteration, Killing, and Lysis of Mycobacterium tuberculosis

The antimycobacterial role of eosinophil peroxidase (EPO), one of the most abundant granule proteins in human eosinophils, was investigated. Our data indicate that purified EPO shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv. On a molar basis, this activity was similar...

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Autors principals: Borelli, Violetta, Vita, Francesca, Shankar, Sandeep, Soranzo, Maria Rosa, Banfi, Elena, Scialino, Giuditta, Brochetta, Cristiana, Zabucchi, Giuliano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC145361/
https://ncbi.nlm.nih.gov/pubmed/12540536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.605-613.2003
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