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Human Eosinophil Peroxidase Induces Surface Alteration, Killing, and Lysis of Mycobacterium tuberculosis

The antimycobacterial role of eosinophil peroxidase (EPO), one of the most abundant granule proteins in human eosinophils, was investigated. Our data indicate that purified EPO shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv. On a molar basis, this activity was similar...

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Main Authors: Borelli, Violetta, Vita, Francesca, Shankar, Sandeep, Soranzo, Maria Rosa, Banfi, Elena, Scialino, Giuditta, Brochetta, Cristiana, Zabucchi, Giuliano
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC145361/
https://ncbi.nlm.nih.gov/pubmed/12540536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.605-613.2003
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