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Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy

Acyclovir, penciclovir, and their prodrugs have been widely used during the past two decades for the treatment of herpesvirus infections. In spite of the distribution of over 2.3 × 10(6) kg of these nucleoside analogues, the prevalence of acyclovir resistance in herpes simplex virus isolates from im...

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Bibliographic Details
Main Authors: Bacon, Teresa H., Levin, Myron J., Leary, Jeffry J., Sarisky, Robert T., Sutton, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC145299/
https://ncbi.nlm.nih.gov/pubmed/12525428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.16.1.114-128.2003
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