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Bypassing complement: evolutionary lessons and future implications
Lectins like mannan-binding protein are part of the innate immune system. They circulate in association with serine proteases. Upon binding oligosaccharides, they activate the complement cascade analogous to the more familiar but evolutionarily more recent classical pathway, which is triggered by an...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1451225/ https://ncbi.nlm.nih.gov/pubmed/16670764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28622 |
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