TGF-β signaling is required for the function of insulin-reactive T regulatory cells

We have previously isolated insulin-reactive Tregs from diabetic NOD mice designated 2H6, from which TCR transgenic mice were generated. The T cells from these 2H6 transgenic mice recognize insulin but have suppressive properties in vitro. They protect NOD mice in vivo from spontaneous development o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Du, Wei, Wong, F. Susan, Li, Ming O., Peng, Jian, Qi, Hao, Flavell, Richard A., Sherwin, Robert, Wen, Li
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2006
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451206/
https://ncbi.nlm.nih.gov/pubmed/16670772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27030
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