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TGF-β signaling is required for the function of insulin-reactive T regulatory cells
We have previously isolated insulin-reactive Tregs from diabetic NOD mice designated 2H6, from which TCR transgenic mice were generated. The T cells from these 2H6 transgenic mice recognize insulin but have suppressive properties in vitro. They protect NOD mice in vivo from spontaneous development o...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1451206/ https://ncbi.nlm.nih.gov/pubmed/16670772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27030 |
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