Adenosine metabolism and murine strain–specific IL-4–induced inflammation, emphysema, and fibrosis

To define the factors that control the tissue effects of IL-4, we compared the effects of Tg IL-4 in Balb/c and C57BL/6 mice. In the former, IL-4 caused modest eosinophilic inflammation and mild airway fibrosis and did not shorten survival. In C57BL/6 mice, IL-4 caused profound eosinophilic inflamma...

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Autori principali: Ma, Bing, Blackburn, Michael R., Lee, Chun Geun, Homer, Robert J., Liu, Wei, Flavell, Richard A., Boyden, Lynn, Lifton, Richard P., Sun, Chun-Xiao, Young, Hays W., Elias, Jack A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451205/
https://ncbi.nlm.nih.gov/pubmed/16670768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26372
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