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Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery

RecA protein is a crucial and central component of the homologous recombination and DNA repair machinery. Despite numerous studies on the protein, several issues concerning its action, including the allosteric regulation mechanism have remained unclear. Here we report, for the first time, a crystal...

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Bibliografiske detaljer
Main Authors: Krishna, R., Manjunath, G. P., Kumar, P., Surolia, A., Chandra, Nagasuma R., Muniyappa, K., Vijayan, M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450331/
https://ncbi.nlm.nih.gov/pubmed/16648362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl107
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