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Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery

RecA protein is a crucial and central component of the homologous recombination and DNA repair machinery. Despite numerous studies on the protein, several issues concerning its action, including the allosteric regulation mechanism have remained unclear. Here we report, for the first time, a crystal...

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Detalhes bibliográficos
Main Authors: Krishna, R., Manjunath, G. P., Kumar, P., Surolia, A., Chandra, Nagasuma R., Muniyappa, K., Vijayan, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450331/
https://ncbi.nlm.nih.gov/pubmed/16648362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl107
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