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The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

Signaling by the mammalian target of rapamycin (mTOR) has been reported to be necessary for mechanical load-induced growth of skeletal muscle. The mechanisms involved in the mechanical activation of mTOR signaling are not known, but several studies indicate that a unique [phosphotidylinositol-3-kina...

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Autores principales: Hornberger, T. A., Chu, W. K., Mak, Y. W., Hsiung, J. W., Huang, S. A., Chien, S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450240/
https://ncbi.nlm.nih.gov/pubmed/16537399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600678103
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