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Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B

Natriuretic peptides (NP) mediate their effects by activating membrane-bound guanylyl cyclase-coupled receptors A (NPR-A) or B (NPR-B). Whereas the pathophysiological role of NPR-A has been widely studied, only limited knowledge on the cardiovascular function of NPR-B is available. In vitro studies...

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Autori principali: Langenickel, Thomas H., Buttgereit, Jens, Pagel-Langenickel, Ines, Lindner, Maren, Monti, Jan, Beuerlein, Knut, Al-Saadi, Nidal, Plehm, Ralph, Popova, Elena, Tank, Jens, Dietz, Rainer, Willenbrock, Roland, Bader, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450239/
https://ncbi.nlm.nih.gov/pubmed/16537417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510019103
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