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Serum response factor MADS box serine -162 phosphorylation switches proliferation and myogenic gene programs

Phosphorylation of a cluster of amino acids in the serum response factor (SRF) “MADS box” αI coil DNA binding domain regulated the transcription of genes associated with proliferation or terminal muscle differentiation. Mimicking phosphorylation of serine-162, a target of protein kinase C-α, with an...

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Detalhes bibliográficos
Main Authors: Iyer, Dinakar, Chang, David, Marx, Joe, Wei, Lei, Olson, Eric N., Parmacek, Michael S., Balasubramanyam, Ashok, Schwartz, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450203/
https://ncbi.nlm.nih.gov/pubmed/16537394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505338103
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