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Serum response factor MADS box serine -162 phosphorylation switches proliferation and myogenic gene programs

Phosphorylation of a cluster of amino acids in the serum response factor (SRF) “MADS box” αI coil DNA binding domain regulated the transcription of genes associated with proliferation or terminal muscle differentiation. Mimicking phosphorylation of serine-162, a target of protein kinase C-α, with an...

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Détails bibliographiques
Auteurs principaux: Iyer, Dinakar, Chang, David, Marx, Joe, Wei, Lei, Olson, Eric N., Parmacek, Michael S., Balasubramanyam, Ashok, Schwartz, Robert J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450203/
https://ncbi.nlm.nih.gov/pubmed/16537394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505338103
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