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S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: Induction by oxidant stress and reversal by reducing agents

Marked increase in cell permeability ascribed to open connexin (Cx)43 hemichannels is induced by metabolic inhibition (MI) of cortical astrocytes in culture, but the molecular mechanisms are not established. Dephosphorylation and/or oxidation of Cx43 hemichannels was proposed as a potential mechanis...

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Detalhes bibliográficos
Main Authors: Retamal, Mauricio A., Cortés, Constanza J., Reuss, Luis, Bennett, Michael V. L., Sáez, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450196/
https://ncbi.nlm.nih.gov/pubmed/16537412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511118103
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