Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population

Inherited mutations in BRCA1 and BRCA2 lead to significantly increased risks of breast and ovarian cancer. We used epidemiologic methods to evaluate the relative risks of breast cancer vs. ovarian cancer among women of Ashkenazi Jewish ancestry with inherited mutations in BRCA1 or BRCA2. The cancer...

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Detalhes bibliográficos
Main Authors: Simchoni, Sharon, Friedman, Eitan, Kaufman, Bella, Gershoni-Baruch, Ruth, Orr-Urtreger, Avi, Kedar-Barnes, Inbal, Shiri-Sverdlov, Ronit, Dagan, Efrat, Tsabari, Sigal, Shohat, Mordechai, Catane, Raphael, King, Mary-Claire, Lahad, Amnon, Levy-Lahad, Ephrat
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450152/
https://ncbi.nlm.nih.gov/pubmed/16537453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511301103
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