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Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

Disrupted-In-Schizophrenia (DISC1) is a leading candidate schizophrenia susceptibility gene. Here, we describe a deletion variant in mDisc1 specific to the 129S6/SvEv strain that introduces a termination codon at exon 7, abolishes production of the full-length protein, and impairs working memory per...

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Detalhes bibliográficos
Main Authors: Koike, Hiroko, Arguello, P. Alexander, Kvajo, Mirna, Karayiorgou, Maria, Gogos, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450143/
https://ncbi.nlm.nih.gov/pubmed/16484369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511189103
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