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A DEAD-box protein alone promotes group II intron splicing and reverse splicing by acting as an RNA chaperone
Group II intron RNAs self-splice in vitro but only at high salt and/or Mg(2+) concentrations and have been thought to require proteins to stabilize their active structure for efficient splicing in vivo. Here, we show that a DEAD-box protein, CYT-19, can by itself promote the splicing and reverse spl...
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Главные авторы: | , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
National Academy of Sciences
2006
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450124/ https://ncbi.nlm.nih.gov/pubmed/16505350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600332103 |
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