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Analysis of the Zebrafish perplexed Mutation Reveals Tissue-Specific Roles for de Novo Pyrimidine Synthesis During Development

The zebrafish perplexed mutation disrupts cell proliferation and differentiation during retinal development. In addition, growth and morphogenesis of the tectum, jaw, and pectoral fins are also affected. Positional cloning was used to identify a mutation in the carbamoyl-phosphate synthetase2-aspart...

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Hlavní autoři: Willer, G. B., Lee, V. M., Gregg, R. G., Link, B. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449754/
https://ncbi.nlm.nih.gov/pubmed/15937129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.041608
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