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Analysis of the Zebrafish perplexed Mutation Reveals Tissue-Specific Roles for de Novo Pyrimidine Synthesis During Development

The zebrafish perplexed mutation disrupts cell proliferation and differentiation during retinal development. In addition, growth and morphogenesis of the tectum, jaw, and pectoral fins are also affected. Positional cloning was used to identify a mutation in the carbamoyl-phosphate synthetase2-aspart...

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Detalhes bibliográficos
Main Authors: Willer, G. B., Lee, V. M., Gregg, R. G., Link, B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449754/
https://ncbi.nlm.nih.gov/pubmed/15937129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.041608
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