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Quantitative Trait Locus Study Design From an Information Perspective

We examine the efficiency of different genotyping and phenotyping strategies in inbred line crosses from an information perspective. This provides a mathematical framework for the statistical aspects of QTL experimental design, while guiding our intuition. Our central result is a simple formula that...

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Autors principals: Sen, Śaunak, Satagopan, Jaya M., Churchill, Gary A.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449722/
https://ncbi.nlm.nih.gov/pubmed/15781700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.038612
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