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Adaptive Molecular Evolution for 13,000 Phage Generations: A Possible Arms Race

Bacteriophage φX174 was evolved on a continuous supply of sensitive hosts for 180 days (∼13,000 phage generations). The average rate of nucleotide substitution was nearly 0.2% (11 substitutions)/20 days, and, surprisingly, substitutions accumulated in a clock-like manner throughout the study, except...

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Detalhes bibliográficos
Main Authors: Wichman, Holly A., Millstein, Jack, Bull, J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449705/
https://ncbi.nlm.nih.gov/pubmed/15687276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.034488
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