Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression

Nitroalkenes are a class of cell signaling mediators generated by NO and fatty acid-dependent redox reactions. Nitrated fatty acids such as 10- and 12-nitro-9,12-octadecadienoic acid (nitrolinoleic acid, LNO(2)) exhibit pluripotent antiinflammatory cell signaling properties. Heme oxygenase 1 (HO-1)...

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Hlavní autoři: Wright, Marcienne M., Schopfer, Francisco J., Baker, Paul R. S., Vidyasagar, Vijay, Powell, Pam, Chumley, Phil, Iles, Karen E., Freeman, Bruce A., Agarwal, Anupam
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449687/
https://ncbi.nlm.nih.gov/pubmed/16537525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506541103
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