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BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability. Homozygous inactivation of BLM gives rise to the cancer predisposition disorder Bloom’s syndrome. A common feature of many RecQ helicase mutants is a hyperrecombination...

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Bibliografiske detaljer
Main Authors: Wu, Leonard, Bachrati, Csanad Z., Ou, Jiongwen, Xu, Chang, Yin, Jinhu, Chang, Michael, Wang, Weidong, Li, Lei, Brown, Grant W., Hickson, Ian D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449647/
https://ncbi.nlm.nih.gov/pubmed/16537486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508295103
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