BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability. Homozygous inactivation of BLM gives rise to the cancer predisposition disorder Bloom’s syndrome. A common feature of many RecQ helicase mutants is a hyperrecombination...

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Autori principali: Wu, Leonard, Bachrati, Csanad Z., Ou, Jiongwen, Xu, Chang, Yin, Jinhu, Chang, Michael, Wang, Weidong, Li, Lei, Brown, Grant W., Hickson, Ian D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449647/
https://ncbi.nlm.nih.gov/pubmed/16537486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508295103
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