Genetic Bases of Estrogen-Induced Pituitary Tumorigenesis: Identification of Genetic Loci Determining Estrogen-Induced Pituitary Growth in Reciprocal Crosses Between the ACI and Copenhagen Rat Strains

Estrogens stimulate proliferation and enhance survival of the prolactin (PRL)-producing lactotroph of the anterior pituitary gland and induce development of PRL-producing pituitary tumors in certain inbred rat strains but not others. The goal of this study was to elucidate the genetic bases of estro...

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Detalhes bibliográficos
Main Authors: Strecker, Tracy E., Spady, Thomas J., Schaffer, Beverly S., Gould, Karen A., Kaufman, Amy E., Shen, Fangchen, McLaughlin, Mac T., Pennington, Karen L., Meza, Jane L., Shull, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449615/
https://ncbi.nlm.nih.gov/pubmed/15687265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039370
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