Genetic Determination of Susceptibility to Estrogen-Induced Mammary Cancer in the ACI Rat: Mapping of Emca1 and Emca2 to Chromosomes 5 and 18

Hormonal, genetic, and environmental factors play major roles in the complex etiology of breast cancer. When treated continuously with 17β-estradiol (E2), the ACI rat exhibits a genetically conferred propensity to develop mammary cancer. The susceptibility of the ACI rat to E2-induced mammary cancer...

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Detalhes bibliográficos
Main Authors: Gould, Karen A., Tochacek, Martin, Schaffer, Beverly S., Reindl, Tanya M., Murrin, Clare R., Lachel, Cynthia M., VanderWoude, Eric A., Pennington, Karen L., Flood, Lisa A., Bynote, Kimberly K., Meza, Jane L., Newton, Michael A., Shull, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448731/
https://ncbi.nlm.nih.gov/pubmed/15611180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033878
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